They are not advised in passenger cars, as per the bag manufacturers.
We use them in LT tires, aka big lifted trucks with 33's on 18's...etc. But I've used them in LT tires such as LT285/75R16 10-ply if the tire is a mud-terrain or Kevlar-sidewall tire just due to the expansive weight off-set between tire and wheel.
They take about 5 miles to break apart(the installation bag) and then counter-balance as you drive. So far, no complaints. They do not harm TPMS sensors, or wheel surfaces. But heaven forbid you need to remove the tire to do a flat repair...Customer will be buying a new bag, and your shop-vac sill have tiny beads inside it....PITA to clean up, but easy to use.